The Wall of Remembrance
Father? Husband?
Son? Best mate?
You can remember a friend or relative on this site by adding your message to our unique Wall of Remembrance
Click here to contribute.
Prostate cancer worries?
Concerned about prostate cancer?
An overview of the disease, symptoms, tests and related useful information.
Helping the Prostate Cancer Research Foundation
Make a donation to the William Franklyn Memorial Fund.
Information on how to help the Prostate Cancer Research Foundation, including donating online, organising your own events and leaving a legacy.
Research Projects
2007 Research Projects
- A double-blind, placebo-controlled, randomised phase II trial of selenium supplementation in men with localised prostate cancer on active surveillance
- Importance of attenuating CXC-chemokine promoted angiogenesis as the mechanistic basis to enhanced Taxotere response in androgen-independent prostate cancer
- Inhibition of androgen signalling in prostate cancer using engineered repressors
- Rational design of ErbB-3 based therapeutics for the treatment of prostate cancer
- Studying the role of NF-kB in prostate cancer - an integrated approach
2006 Research Projects
Peter Gardner and his team at the University of Manchester
- Development and assessment of targeted radionuclide combined with death inducing and growth inhibiting immunotherapy for potential treatment of hormone refractory prostate cancer.
- Isolation, culture and molecular characterisation of castration-refractory prostate cancer (CRPC) stem cells from clinical tumour material.
- Importance of Interleukin-8 signalling as a mode of resistance of prostate cancer cells to ionizing radiation.
- Endogemous anti-angiogenic tumour suppressing VEGF splice variants in the treatment of prostate cancer.
- A gene therapy strategy for metastatic prostate cancer: use of a novel molecular switch for transcriptional targeting of iNos.
- Development of oncolytic adenoviruses for targeting of androgen-independent prostate cancers: enhancement of anti-tumour efficacy by combination therapies.
- Investigation of environmental, lifestyle and genetic risk factors for prostate cancer in younger men.
- PCRF Clinical Research Fellowship, working on the project Prostate cancer proliferation cell markers.
2005 Research Projects
- RNA interference as a potential utility for prostate cancer therapy
- Novel Chemotherapeutic Peptides – Targeting the Cell Membrane>
- A Novel Mediator of Androgen Receptor Degradation in Hypoxic prostate carcinoma cells
- Finding genes that predispose to prostate cancer
- Combined Optical Tweezers and Near IR Spectroscopy for Prostate Cancer Diagnosis
2004 Research Projects
Prostate Cancer Research Foundation currently funds 17 research projects around the world
- IGF1R in Prostate Cancer
- Do functional Seleno-protein SNPs predict PC?
- Nitric oxide – voltage-gated Na + channel interaction in prostate cancer metastasis
- Is the PI3K/Akt pathway involved in hormone refractory prostate cancer?
- Cyto-Raman Microscopy in Prostate Cancer
- Novel Anti-prostate cancer drugs
2003 Research Projects
- Screening Telomerase Activity in cancer cells
- Investigating the effect of manipulation of Poly (ADP-Ribose) Polymerase-1 (PARP-1) on the response of prostate carcinoma cells to low dose rate eradication
- The prognosic role of intrinsic markers of tumour hypoxia and angiogenesis.
- Screening of prostate cancer by the ultra sensitive bioelectronic detection of telomerase activity.
